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How does EndoStim work?

GERD and associated symptoms are often caused by a dysfunctional lower esophageal sphincter (LES) valve between the stomach and the esophagus. The EndoStim neurostimulation system delivers mild electrical signals to the LES automatically throughout the day. This gentle stimulation is designed to restore normal function to the LES, and normally cannot be felt by patients.

EndoStim gently stimulates the LES valve to allow it to function normally again – stay closed to prevent reflux, open to allow for food and drink to pass into the stomach.

The EndoStim System

The EndoStim System consists of a neurostimulator (IPG), implantable bipolar lead and wireless external programmer (used in clinic). The IPG delivers stimulation therapy to the LES via the lead. The device battery is expected to last approximately 7 (Gen 2 device) or 10 (Gen 1 device) years under recommended stimulation algorithms.

The IPG and lead are placed through a minimally-invasive laparoscopic procedure. After the procedure, the EndoStim device is programmed wirelessly by a physician. The stimulation therapy can, if needed, be adjusted at future follow-up visits by a physician.

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